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Dilaudid (hydromorphone) is a schedule II controlled substance prescribed for moderate to severe pain. The drug attaches to receptors in the brain and central nervous system to dull pain. Dilaudid also triggers the release of excessive amounts of dopamine in the brain, causing pleasurable feelings. This activates the reward center of the brain, which interprets the event as something that is important and should be repeated. The more this happens, the less the brain will naturally produce dopamine, and the more reliant the body becomes on Dilaudid. Buy Dilaudid Online
Like other opioids, Dilaudid produces euphoria, feelings of relaxation, reduced anxiety, respiratory depression, sedation, constipation, papillary constriction, and cough suppression. Acute overdose can produce severe respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, reduction in blood pressure and heart rate, and death. Pure opioid antagonists such as naloxone work as antidotes to hydromorphone overdose. Buy Dilaudid Online
DOSAGE AND ADMINISTRATION
Important Dosage And Administration Instructions
- Ensure accuracy when prescribing, dispensing, and administering DILAUDID Oral Solution to avoid dosing errors due to confusion between mg and mL, which could result in accidental overdose and death. Ensure the proper dose is communicated and dispensed. When writing prescriptions, include both the total dose in mg and the total dose in volume.
- Instruct patients to obtain a calibrated measuring cup/syringe for administering DILAUDID Oral Solution to ensure that the dose is measured and administered accurately.
- Do not use household teaspoons or tablespoons to measure DILAUDID Oral Solution, as using a
- Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals
- Initiate the dosing regimen for each patient individually, taking into account the patient’s severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse
- Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy and following dosage increases with Dilaudid Oral Solution or Dilaudid Tablets and adjust the dosage accordingly
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.
Serious adverse reactions associated with DILAUDID include respiratory depression and apnea and, to a lesser degree, circulatory depression, respiratory arrest, shock, and cardiac arrest.
The most common adverse effects are lightheadedness, dizziness, sedation, nausea, vomiting, sweating, flushing, dysphoria, euphoria, dry mouth, and pruritus. These effects seem to be more prominent in ambulatory patients and in those not experiencing severe pain.
DILAUDID Oral Solution and Dilaudid Tablets are contraindicated in patients with:
- Significant respiratory depression
- Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment
- Known or suspected gastrointestinal obstruction, including paralytic ileus
- Hypersensitivity to hydromorphone, hydromorphone salts, any other components of the product, or sulfite-containing medication
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